Omics: The Next Revolution in Medicine

May 15, 2021 to May 16, 2021
The field of omics is a rapidly evolving, multi-disciplinary, and emerging one that encompasses genomics, epigenomics, transcriptomics, proteomics, and metabolomics. Each of these individual fields offers the possibility to understand and personalize patient care in a way that was previously unthinkable.
 
Research has demonstrated how epigenetics play a critical role in turning genes on and off—illustrating that a person's genes need not define their medical future. But how can clinicians practically make use of this knowledge? A few years ago obtaining a patient’s genomic sequence was cost-prohibitive and the clinical application was not detailed based on the genetic information obtained. But today real clinical applications and guidance are available to improve patient health and wellbeing.
 
During this workshop participants will examine these cutting-edge applications as well as the quickly evolving research surrounding the science of omics.
 
Any technical or CME related questions should be sent to cehp@gwu.edu 
 
Should you have any questions about the content or faculty please email program@a4m.com.
 
The faculty disclosures can be found under "Additional Information" below.
 
To Begin, select "Start"

Target Audience

This course is designed for physicians (internal medicine, family medicine, endocrinologists, general medicine, and OB-GYN), pharmacists, physician assistants, nurses, nurse practitioners, and other healthcare professionals interested in learning about the advancements of preventative and anti-aging medicine.

Learning Objectives

  • Define the similarities and differences between the fields of genetics and genomics.
  • Examine the influences that affect gene expression including epigenetics, transgenerational epigenetics, endogenous transcription factors and proper sequencing of gene expression from gene to small molecule.
  • Explore the technical aspects and challenges to the laboratory sciences of OMICS.
  • Review CPIC guidelines and clinical application.
  • Review various genetic and epigenetic reports and their interpretation.
  • Review various genetic information regarding methylation, detoxification, metabolism pathways and way to influence wellness with actional steps to modify disease states.
  • Review specific genetic analysis for estrogen metabolism, inflammation, diet

Additional Information

AttachmentSize
PDF icon Omics - Faculty Disclosures148.1 KB
PDF icon Omics Schedule181.58 KB
Course summary
Available credit: 
  • 14.50 AMA PRA Category 1 Credit™
    The George Washington University School of Medicine and Health Sciences is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
  • 14.50 Completion
Course opens: 
05/13/2021
Course expires: 
08/15/2021
Event starts: 
05/15/2021 - 9:00am
Event ends: 
05/16/2021 - 6:30pm
Rating: 
0

Lucia Aronica, PhD

Dr. Lucia Aronica, Ph.D., is Lecturer at the Stanford Prevention and Research Center, and R&D Lead, Genomics, at Metagenics Inc. Her research and teaching focus on how lifestyle can change gene expression through a process called epigenetics, and how we can use this information to design personalized lifestyle interventions for optimal health and longevity. Some topics of her courses include nutrigenomics and nutrigenetics, intermittent fasting and ketogenic diets, and the role of these interventions in personalized lifestyle medicine and longevity medicine. She has published research papers in top-ranked peer-reviewed journals such as JAMA, The American Journal of Clinical Nutrition, Cell, and Genes and Development. More information about Dr. Aronica’s courses at Stanford is available at: https://draronica.com/
 
Sanjeev Goel, MD, FCFP(PC), CAFCI
 
Dr. Sanjeev Goel is a practicing medical physician and the founder of Peak Human, a practice dedicated to helping his patients live 100x their potential NOW. He believes in a holistic approach to wellness as has done training in Anti-Aging, Integrative and Regenerative Medicine. He advocates a healthy lifestyle centered around plant based diet, focused physical activity and enhancing mental resilience. He also runs a medical cannabis clinic called Canadian MedCanna Clinics in Brampton, Ontario.
 
Dr. Goel's journey on understanding the potential of psychedelic medicine to heal ourselves begin with a providing psychotherapy to those suffering from trauma, anxiety, depression and eating disorders.  Over the past 20 years, he has taught mindfulness and published a book called "Awakening from a Mindless Life".
Dr. Goel believes that we should have access to the best medical and health technologies available. Prior to Peak Human, he led the development of the largest patient health portal in Canada called midash and hosted the first ever Biohacker Summit in Toronto (Oct 2018) bringing culture, technology and health together.
 
Andrew Heyman, MD, MHSA 
 
Dr. Heyman is an internationally recognized expert in Integrative Medicine. He is currently the Program Director of Integrative and Metabolic Medicine at The George Washington University. Prior to assuming this role, he spent 16 years at the University of Michigan, serving to build one of the largest and most successful academic-based Integrative Medicine programs in the United States.
In 1990, he received formal training in Five-element Shiatsu and Traditional Chinese Medicine, during which time he developed an interest in increasing access of natural therapies to underserved populations while partnering with the University of Pennsylvania. He continued this work with Jim Gordon, MD at the Center for Mind-Body Medicine in Washington DC exploring the intersection between public health, at risk groups, and alternative therapies.

Dr. Heyman eventually went on to receive a Masters in Health Services Administration at the University of Michigan School of Public Health and upon graduation, became the administrator for the University of Michigan Complementary and Alternative Medicine Research Center where he was responsible for administering a $7 million NIH grant to research alternative therapies for cardiovascular diseases. The center was one of the first in the country to place alternative therapies and their scientific examination in an academic context.

Dr. Heyman has held several leadership positions in the field of Integrative Medicine. He was the national clinical working group co-chair of the Consortium of Academic Health Centers for Integrative Medicine for 4 years, a collaboration of 57 North American universities involved in Integrative Medicine. He is the online editor for the Journal of Men's Health in the section of Integrative Medicine, and he also holds the position of Editor-In-Chief of the Internet Journal of Anti-Aging and Aesthetic Medicine. His research interests include the Stress response and NeuroEndocrinology, Cardiometabolic Disease, Men's Health, and clinical outcomes research methodologies.

Dr. Heyman remains clinically active as well, as the owner of a four-physician integrative medicine practice in Northern Virginia at the Virginia Center for Health and Wellness. He is also the President of Integrative Health Resources, a small group of clinical experts that consults to physicians, health systems, and public health professionals seeking to develop wellness, lifestyle, and nutrition programs. Finally, Dr. Heyman has been featured on the Discovery Channel, Martha Stewart Living Magazine, Ladies Home Journal, Natural Health Magazine, and appeared in many other TV and print venues and is a widely sought after, and celebrated speaker around the world on many Integrative Medicine topics. His teaching approach is described as deeply rooted in scientific evidence, grounded in the clinical reality of expert patient care, and readily accessible to both the new learner and seasoned practitioner alike.

Todd LePine, MD

Dr. Todd LePine graduated from Dartmouth Medical School and is Board Certified in Internal Medicine, specializing in Integrative Functional Medicine. Additionally, he has advanced clinical training through the Institute for Functional Medicine. Dr. LePine is a staff physician with Dr. Mark Hyman at The UltraWellness Center located in Lenox, Massachusetts in the Berkshires. Prior to joining the UltraWellness Center Dr. LePine worked as a staff physician at Canyon Ranch Health Spa in Lenox, Massachusetts consulting with patients from around the world looking for optimal health.
 
He is a faculty member of the American Academy of Anti-Aging Medicine and a consultant for Designs for Health. His areas of interest within medicine include: The Human Microbiome and its effect in health and disease, the neurobiology of mood and cognitive disorders. NutriGenomics, Optimal Aging, Autoimmune diseases and Detoxification.

Helen Messier, PhD, MD, CCFP

Dr. Helen Messier’s focus is on closing the translational gap using a data-driven healthcare model. This real-time translation of precision medicine integrates multi-omics technologies and applies them directly in clinical care, allowing patients with complex chronic disease to actively benefit from innovative biomedical technologies. Dr. Messier received a bachelor of science (hons.) in genetics and a PhD in molecular immunology from the University of Alberta. She completed post-doctoral studies at the La Jolla Institute for Allergy and Immunology in San Diego, CA, received her MD from the University of Calgary, and is certified in family medicine. She founded a series of national concierge practices, served as a medical director, genomics, at HLI, and was CMO of Viome. Her strong scientific and medical background is combined with a passion for helping people realize their optimal level of health and in teaching others to apply complex molecular data to the care of individuals. Dr. Messier is currently at Altum Medical, a center that provides deep dive medical care, and is the founder of Medical Intelligence Learning Labs Inc., a company that is creating a platform to enable every doctor to be “the best” doctor by capturing the clinical wisdom from every medical encounter so it can be accessed by the larger medical community.

Daniel Meyersfeld, PhD

Dr. Daniel Meyersfeld completed his PhD in molecular biology at the University of the Witwatersrand, South Africa, in 2005. During his studies, he saw an opportunity to use recent advances in the field of human genetics to improve people’s health and wellness and established DNAlysis Biotechnology in 2007. The company is now recognized as a global leader in the field of biotechnology, with an established practitioner following in South Africa, Scandinavia, Europe, Far East, Middle East and the USA.

Mansoor Mohammed, BCS, PhD

Dr. Mohammed is the Founder and President of ManaGene, considered one of the most innovative leaders in the emerging personalized medicine and lifestyle genomics space. 
Dr. Mohammed is widely regarded as a pioneer in medical genomics and has been the recipient of multiple academic and industry awards. He is the holder of several patents in the general fields of molecular diagnostics and genomics research, and is one of the most sought-after national and international conference speakers in the genre of personalized medical genomics.
 
While completing his clinical post-doctoral internship at the University of California, Los Angeles (UCLA), Dr. Mohammed was credited with discovering one of two genomic pathways that define drug resistance to the Novartis-developed leukemia therapy, Gleevec, and co-published these findings in the journal Science (2001) with the renowned oncologist Dr. Charles Sawyers. That same year, he was the co-author of the American Society of Human Genetics’ Paper of the Year Award with his mentor, Dr. Eric Vilain, for their discovery of the role of the Wnt4 gene in sex-reversal. These early studies helped to define Dr. Mohammed as one of the few genomic specialists with core competencies in both the genomic characteristics of childhood development, as well as the genomic etiology of oncology/cancer.
 
Concomitant with his postdoctoral fellowship at Baylor College of Medicine (2001), Dr. Mohammed was instrumental in the development and commercialization of the industry’s first available comparative genomic hybridization (CGH) arrays. He has since been widely regarded as one of the primary innovators in the diagnostic application of genomic microarrays and has contributed to seminal studies in that field. He was the co-primary author of the first peer-reviewed study utilizing microarray CGH techniques in the clinical diagnosis of developmental abnormalities (2002) and later (2008) was the senior author of the first peer-reviewed study utilizing microarray CGH techniques for clinical oncology purposes. The CGH technologies that Dr. Mohammed helped to develop and commercialize have continued to revolutionize the understanding of the human genome and have spawned thousands of peer-reviewed papers across the international academic community. Considered by Dr. Mohammed as one of the early highlights of his career, and in recognition of his contributions to developing genomic microarray technologies, he was invited as a plenary speaker to commemorate the 50th anniversary of the discovery of the DNA double helix at the world Human Genome Organization meeting (Cancun, Mexico 2003).
Dr. Mohammed was a founder (2001) and Director of Research and Development at Spectral Genomics Inc. Under Dr. Mohammed’s scientific stewardship, Spectral Genomics quickly grew from a start-up funded by Baylor College of Medicine, to an authority in the emerging field of medical comparative genomics and was eventually acquired by PerkinElmer Inc.
 
With the acquisition of Spectral Genomics, Dr. Mohammed was invited to head the (then) newly established Advanced Technologies Department at North America’s largest diagnostics reference laboratory, Quest Diagnostics Inc. (2003-2006). Overseeing a state-of-the-art facility at Quest, he was responsible for designing the roadmap and executing the adoption of new diagnostic technologies for this Fortune 500 Company (Market Capitalization exceeding 8 billion US). Within his first year at Quest, Dr. Mohammed was honored with the Patent Innovation Award for prolific innovations and discoveries and notably during his tenure was the youngest recipient of the Medical Innovation Award: Quest’s highest and most prestigious employee recognition award.
In 2006, Dr. Mohammed was recruited to co-found and lead the development of Combimatrix Molecular Diagnostics (CMDX). He served as the latter’s Chief Scientific Officer, Chief Operating Officer and for his last 4 years of tenure, as Chief Executive Officer. Under his leadership, CMDX became the first diagnostic company offering genomic microarray-based diagnostics to receive an official “freedom to operate” clearance by the FDA. Moreover, under his guidance, CMDX developed and launched the most comprehensive portfolio of clinically validated genomics based tests in the industry and witnessed 9 consecutive quarters of financial growth with its stock price growing from ~$4/share to over $16/share (Nasdaq).
After a decade of intense professional growth, and with an extensive network of academic, clinical and industrial colleagues, Dr. Mohammed left CMDX in October 2010 to pursue the launch of his own firm, ManaGene Inc. ManaGene is focused on providing best-in-class consulting services to the personalized medicine and genomic diagnostic service sectors. It capitalizes on Dr. Mohammed’s unique breadth and depth of experience to help companies and clinics navigate through the complex ecosystem characteristic of personalized medicine and diagnostics ventures. ManaGeneD counts as its clients, medical clinics, diagnostic companies and research institutes in the US, Canada, Europe, Asia and the Middle East.
 
Dr. Mohammed has served on the Canadian Board of Autistic Research and is a consultant to the world-renowned Toronto Center of Applied Genomics. He has had the honor of being the personal guest of the former Premiere of Ontario, the Honorable Dalton McGuinty, and on several occasions, the guest of the Canadian Consulate of California. He has also sat on several think tank panels, including ones from the FDA and National Institute of Health (NIH) and is a frequent academic lecturer on the role of genomics in medicine.

 

 

 

 

 

      

Michele L. Neil-Sherwood, DO and Mark Sherwood, ND

Mark Sherwood, Naturopathic Doctor (ND) and Michele L. Neil-Sherwood, Doctor of Osteopathy (DO) are trailblazers and pioneers in functional healing utilizing cutting edge treatment protocols that have led to hundreds of amazing healing testimonials.  They have a full-time wellness-based medical practice in Tulsa, OK called the Functional Medical Institute where they adopt a whole person approach, which is outcome based looking at each individual’s unique needs. With a huge vision to change the world health care crisis one person at a time, their mission is to lead people down a pathway of true healing. To that end, there are two purposes: 1. To eradicate all self-imposed, choice driven disease conditions, and 2. To eliminate the usage of unnecessary medications. Through their unique clinic, various diagnostic tests are used, including genetics, bio-impedance, neurotransmitter, vascular aging, and stress management. The couple host a weekly television program airing regionally in the Midwest US. They serve patients in nearly every state in the US and in several countries around the world.
 
Drs. Mark and Michele co-authored several books, including the Amazon best-sellers, The Quest for Wellness, Fork Your Diet, and Surviving the Garden of Eatin’. They have been seen on national TV, been quoted on CNN, and are regular contributors to many national publications.  With a broad social media network that spans the globe, Drs. Mark and Michele’s influence is broad, reaching over 2 million people annually. Their first full-length movie entitled, Fork your Diet – the movie, has over 15 million minutes viewed worldwide and is available on Amazon. Their second movie, The Prayer List, based on Dr. Michele’s life story, was recently released for worldwide distribution.  
 
Dr. Michele is double board certified (internal medicine and sports medicine) and specializes in the following disciplines: Age Management Medicine, Nutrigenetics and Nutrigenomics, Naturopathic and Functional Medicine, Lifestyle Coaching, Prolotherapy, and Osteopathic Manipulative Therapy. She has an extensive fitness and athletic background including martial arts (brown belt - Judo, Black belt - Tae-Kwon-Do), physique titles, and multiple body movement systems (e.g. Russian kettlebells). Michele is a true trailblazer in all aspects of wellness and excels in leading persons down a pathway of true healing. 
 
Dr. Mark has completed training and certifications in age management, functional medicine, nutrigenetics, nutrigenomics, hormone therapy, peptide therapy, stress management, GI health, and immunology. He is a 24-year retired veteran of the Tulsa Police Department, where he logged a decade of courageous service on the department’s SWAT Team. He is also a former Oklahoma state and regional physique champion, and ex-professional baseball player. Dr. Mark’s passion for wellness has led to him speaking to millions, both in person and on television worldwide. Mark is a licensed minister and motivational speaker whose presentations are sought by audiences nationwide. His passion and experience for total wellness make him a versatile role model for people of all ages.
 
The couple understands the importance of nutrition, medical food & supplementation, exercise prescription, rest, stress management, hormone balance and functional movement. This makes them a modern day “dynamic duo of wellness.”

Amy Pasternak, PharmD

Dr. Pasternak received her PharmD from Ohio Northern University in 2014. Following graduation she completed a PGY-1 general pharmacy practice residency at Cleveland Clinic Hillcrest Hospital in Mayfield Heights, OH and a PGY-2 Clinical Pharmacogenetics pharmacy residency at St. Jude Children’s Research Hospital in Memphis, TN. After completing her clinical pharmacy training, Dr. Pasternak became a Clinical Pharmacy Translational Science Fellow at the University of Michigan College of Pharmacy. She joined the faculty at the University of Michigan College of Pharmacy as a Clinical Assistant Professor in 2018. Dr. Pasternak’s clinical and research practice are both centered around the implementation pharmacogenetics.

James Ryan, PhD

Dr. Ryan is a Clinical Research Scientist focused on diagnostic tools and therapies for chronic inflammation initiated by a wide variety of biotoxins, such as Lyme disease, ciguatera fish poisoning, sick building syndrome and others. Dr. Ryan is a graduate of the Medical University of South Carolina, and holds Bachelor’s degrees in biology, chemistry and physics. He is a co-founder in the medical diagnostics company Progene DX, LLC: which uses cutting-edge genomic technologies to identify pathophysiology in a personalized medicine setting. Dr. Ryan’s recent investigation into Chronic Inflammatory Response Syndrome (CIRS) has led to the development of a gene expression assay that is currently being commercialized in order to track metabolic shifts in patients with chronic fatiguing illnesses.

Daniel Stickler, MD

He is the Co-Founder and Chief Medical Officer of The Apeiron Center for Human Potential and Chief Science Officer for Apeiron Academy. He is the pioneer behind systems-based precision performance medicine, a new paradigm that re-defines medicine from the old symptoms based disease model to one of limitless peak performance in all aspects of life. A physician to high-performing executives and entrepreneurs who want to upgrade their current state, he’s also an author, speaker, blogger and podcaster. He is the Medical Director for the Neurohacker Collective, a Google consultant for wearable technology, epigenetics, and AI in healthcare and a guest lecturer at Stanford University on Epigenetics in Clinical Practice. In 2008, a new world opened through the lens of genetics and epigenetics and his near obsession like fascination of the potentials for personalized human systems design led to the realization that we truly have the ability within us to take charge of our destiny and become the architects of our evolution. 

Jessica Su, ScD, MS

Dr. Lasky-Su is an Associate Professor in Medicine and Associate Statistician at Harvard Medical School and Brigham and Women’s Hospital. Over the last 21 years, Dr. Lasky-Su has focused on the analysis of genetics, genomics, and metabolomics data of various complex diseases with a primary focus on respiratory disease over the last 16 years. The accumulation of these efforts has resulted in a productive track record of over 170 original research articles. Through the funding of multiple metabolomics-related grants, Dr. Lasky-Su has developed a “metabolomic epidemiology” research program at the Channing Division of Network Medicine that has been highly successful and synergistic in nature, and has developed into one of the largest and most impactful groups of metabolomic epidemiologists with a strong national and international presence and comprehensive publication record. In addition to using metabolomics to study the etiology of several complex diseases, including body mass index, asthma, allergies, autism, bacteremia, and macular degeneration, Dr. Lasky-Su has also focused on using metabolomics data in conjunction with other omics data to study disease etiology using several approaches to integrative omics. Most recently, Dr. Lasky-Su is applying her expertise in metabolomics to understand the biologic determinants of a severe COVID-19 response and to develop a predictive prognostic test to identify those at risk of a severe COVID-19 response. She serves in national and international leadership capacities, including the President of the Metabolomics Society, the chairman of the Consortium of METabolomic Studies (COMETS), and a governing board member of the “Metabolomics Workbench.”

Filomena Trindade, MD, MPH, ABAARM, ABFM, FMNM

Dr. Trindade is a teacher, author, and international speaker in functional medicine. She is a graduate of the fellowship in Anti-Aging, Regenerative and Functional Medicine and teaches in the Fellowship (a Master’s program through the Morsani School of Medicine, University of South Florida).
 
After obtaining her BA degree in Biology she went on to finish a Master’s in Public Health in the area of environmental health and epidemiology before starting medical school. She graduated first in her class in family practice from the University of California Davis School of Medicine and did her residency training in family practice at the U.C. San Francisco/Santa Rosa Program. She has been in clinical practice for over 20 years. Before starting her own private practice in 2004 in functional medicine she was the medical director of a non-profit organization that catered to the underserved. Her work has been published in Townsend Letter, Guide to Anti-Aging & Regenerative Medicine, Saúde Actual, and the Border Health Journal among others. She is currently very active in developing teaching programs in Functional Medicine in the USA, Latin America and Europe. Keep up with her activities at www.drtrindade.com.

Available Credit

  • 14.50 AMA PRA Category 1 Credit™
    The George Washington University School of Medicine and Health Sciences is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
  • 14.50 Completion
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