Menopausal Hormone Therapy:  Just about Everything you Believe about Breast Cancer is Wrong

James Simon MD

Clinical Professor

Department of Obstetrics and Gynecology

The George Washington University

Learning Objectives:

Menopausal Hormone Therapy: Just about Everything you Believe about Breast Cancer is Wrong!

James A. Simon, MD, CCD, NCMP, IF, FACOG

Learning Objectives:

Upon completion of this lecture participants should be able to:

v Apply relevant data and not media hyperbole to educate patients and fellow practitioners guiding them through menopausal hormone therapy decision making related to breast cancer.

v Understand that “spin” and “alternative facts” are pervasive in science, and that the NIH, WHI, and FDA are not immune to these phenomena.

v Appreciate that the mainstream media (broadcast, print and social) have been lazy at best, complicit and irresponsible at worse, in reporting the risks and benefits of menopausal hormone therapy, generally, but particularly as related to breast cancer risks.

v Apply the processes of growth promotion/deceleration, SERM action, hormesis, and apoptosis to the effects of estrogens/progestogens on the appearance of breast cancer risk.

v Have a better appreciation of and appropriate context for the true risks of breast cancer related to menopausal hormone therapy.

Disclosures: 

Disclosures Fall 2022 and for the previous 36 months.

Advisory Boards/Consultant: Bayer Healthcare, Besins Healthcare, California Institute of Integral Studies (CIIS), Camargo Pharmaceutical Services, Covance Inc., Dare´ Bioscience, DEKA M.E.L.A S.r.l., Femasys, KaNDy/NeRRe Therapeutics, Khyria, Madorra, Mitsubishi Tanabe Pharma Development America, QUE Oncology, Scynexis Inc, Sebela Pharmaceuticals, Sprout Pharmaceuticals, Vella Bioscience.

Grants/Research: AbbVie, Bayer Healthcare, Dare´Bioscience, Enteris BioPharma, Ipsen, Mylan/Viatris, Myovant Sciences, ObsEva, Sebela Pharmaceuticals, Viveve Medical

Speaker: Mayne Pharma, Myovant Sciences, Pfizer, Pharmavite, Scynexis, TherapeuticsMD.

For all consulting: fees were paid to me at fair market value.

For all grants and Research: fees were paid to IntimMedicine Specialists for clinical trial work.

For all speaker activities: fees were paid to me at fair market value.